The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2008
Filed:
Jan. 12, 2005
Ameriga Lazzarini, Legnano, IT;
Luciano Gastaldo, Pogliano Milanese, IT;
Gianpaolo Candiani, Gorgonzola, IT;
Ismaela Ciciliato, Busto Arsizio, IT;
Daniele Losi, Rovellasca, IT;
Flavia Marinelli, Milan, IT;
Enrico Selva, Gropello Cairoli, IT;
Franco Parenti, Lainate, IT;
Ameriga Lazzarini, Legnano, IT;
Luciano Gastaldo, Pogliano Milanese, IT;
Gianpaolo Candiani, Gorgonzola, IT;
Ismaela Ciciliato, Busto Arsizio, IT;
Daniele Losi, Rovellasca, IT;
Flavia Marinelli, Milan, IT;
Enrico Selva, Gropello Cairoli, IT;
Franco Parenti, Lainate, IT;
Vicuron Pharmaceuticals Inc., King of Prussia, PA (US);
Abstract
The invention relates to an antibiotic substance of microbial origin, arbitrarily denominated antibiotic 107891 which is produced by fermentation ofsp. ATCC PTA-5024, the pharmaceutically acceptable salts and compositions thereof, and their use as an antibacterial agent having inhibitory activity versus susceptible microbes. Antibiotic 107891, which is a complex comprising two Factors, denominated Factors A1 and A2, has a peptide structure containing lanthionine and methyllanthionine as constituents which are typical characteristics of the antibiotics of the lantibiotics group. Antibiotic 107891 and its Factors A1 and A2 show a good antibacterial activity against Gram-positive bacteria including methicillin resistant and vancomycin resistant strains, and is active also against some Gram-negative bacteria such asspecies andand