The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7318924 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 15, 2008

Filed:

Mar. 26, 2002
Applicants:

Ian Farquhar Campbell Mckenzie, Point Lonsdale, AU;

Pei-xiang Xing, Heidelberg Heights, AU;

Xiu Feng HU, Heidelberg Heights, AU;

Inventors:

Ian Farquhar Campbell McKenzie, Point Lonsdale, AU;

Pei-Xiang Xing, Heidelberg Heights, AU;

Xiu Feng Hu, Heidelberg Heights, AU;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

An isolated binding partner of a Cripto-1 protein, Pim-1 protein or an antigen present in a colon cancer cell lysate is described. The binding partner inhibits growth of one or more cancer cell types and may be used in an anti-cancer agent for treating cancer in a subject. The binding partner may also be used in a method of inducing apoptosis in a cancer cell, as well as in a method of sensitizing a cancer cell to a cytotoxic compound. In addition, a cancer vaccine is described wherein the vaccine comprises a Cripto-1 protein (or an antigenic fragment thereof), Pim-1 protein (or an antigenic fragment thereof) or an antigen present in a colon cancer cell lysate or, alternatively, comprises an expressible DNA molecule encoding a Cripto-1 protein (or an antigenic fragment thereof), Pim-1 protein (or an antigenic fragment thereof) or an antigen present in a colon cancer cell lysate.


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McKenzie, Ian Farquhar Campbell. (2008). Antibodies against cancer (U.S. Patent No. 7318924). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7318924

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