The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2008

Filed:

Mar. 04, 2004
Applicants:

Samuel Fournier Lockwood, Lake Linden, MI (US);

Sean O'malley, Honolulu, HI (US);

David G. Watumull, Honolulu, HI (US);

Laura M. Hix, San Francisco, CA (US);

Henry Jackson, Honolulu, HI (US);

Geoff Nadolski, Kaaawa, HI (US);

Inventors:

Samuel Fournier Lockwood, Lake Linden, MI (US);

Sean O'Malley, Honolulu, HI (US);

David G. Watumull, Honolulu, HI (US);

Laura M. Hix, San Francisco, CA (US);

Henry Jackson, Honolulu, HI (US);

Geoff Nadolski, Kaaawa, HI (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/34 (2006.01); A61K 31/40 (2006.01); A61K 31/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of treating ischemic reperfusion injury in a subject. The method may include administering to the subject an effective amount of a pharmaceutically acceptable formulation. The pharmaceutically acceptable formulation may include a synthetic analog or derivative of a carotenoid. The subject may be administered a carotenoid analog or derivative, either alone or in combination with another carotenoid analog or derivative, or co-antioxidant formulation. The carotenoid analog may include a conjugated polyene with between 7 to 14 double bonds. The conjugated polyene may include a cyclic ring including at least one substituent. In some embodiments, a cyclic ring of a carotenoid analog or derivative may include at least one substituent. The substituent may be coupled to the cyclic ring with an ester functionality.


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