The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2008

Filed:

Apr. 24, 2002
Applicants:

Erwin Sablon, Merchtem, BE;

Annie Van Broekhoven, Berchem, BE;

Fons Bosman, Opwijk, BE;

Erik Depla, Destelbergen, BE;

Geert Deschamps, Aalter, BE;

Inventors:

Erwin Sablon, Merchtem, BE;

Annie Van Broekhoven, Berchem, BE;

Fons Bosman, Opwijk, BE;

Erik Depla, Destelbergen, BE;

Geert Deschamps, Aalter, BE;

Assignee:

Innogenetics N.V., Ghent, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C12P 21/00 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12N 15/51 (2006.01); A61K 39/00 (2006.01); A61K 39/29 (2006.01);
U.S. Cl.
CPC ...
Abstract

The current invention relates to vectors and methods for efficient expression of HCV envelope proteins in eukaryotic cells. More particularly said vectors comprise the coding sequence for an avian lysozyme signal peptide or a functional equivalent thereof joined to a HCV envelope protein or a part thereof. Said avian lysozyme signal peptide is efficiently removed when the protein comprising said avian lysozyme signal peptide joined to a HCV envelope protein or a part thereof is expressed in a eukaryotic cell. Suitable eukaryotic cells include yeast cells such asorcells.


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