The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2008
Filed:
Apr. 19, 2006
Elizabeth Singer, Duarte, CA (US);
Ralf Landgraf, Van Nuys, CA (US);
Dennis J. Slamon, Woodland Hills, CA (US);
David Eisenberg, Los Angeles, CA (US);
Elizabeth Singer, Duarte, CA (US);
Ralf Landgraf, Van Nuys, CA (US);
Dennis J. Slamon, Woodland Hills, CA (US);
David Eisenberg, Los Angeles, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The disclosure provided herein identifies and characterizes the domain in HER3 receptor that interacts with heregulin ligand. Typical embodiments of the invention disclosed herein include HER3 variant polypeptides having amino acid sequences which differ from the native HER3 polypeptide sequence and which have altered affinities for heregulin. Also disclosed herein are methods and materials for identifying compounds that bind to the heregulin binding domain in HER3 as well as methods and materials for modulating the interaction between HER3 and heregulin.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile