The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2008
Filed:
Mar. 03, 2004
Seiichi Sato, Suginami-ku, JP;
Tomoyuki Koshi, Shiki, JP;
Toshimi Mizoguchi, Iruma, JP;
Kyoko Yasuoka, Higashiyamato, JP;
Natsuyo Kumai, Fujimi, JP;
Junko Totsuka, Nerima-ku, JP;
Masahiro Tamura, Machida, JP;
Masao Ohkuchi, Tokorozawa, JP;
Seiichi Sato, Suginami-ku, JP;
Tomoyuki Koshi, Shiki, JP;
Toshimi Mizoguchi, Iruma, JP;
Kyoko Yasuoka, Higashiyamato, JP;
Natsuyo Kumai, Fujimi, JP;
Junko Totsuka, Nerima-ku, JP;
Masahiro Tamura, Machida, JP;
Masao Ohkuchi, Tokorozawa, JP;
Kowa Co., Ltd., Nagoya-shi, JP;
Abstract
The present invention is directed to a compound represented by formula (1): (wherein Rrepresents an alkyl group which may have a substituent or an alkenyl group which may have a substituent; and each of Rand Rrepresents a hydrogen atom, an alkyl group, a hydroxyalkyl group, a dihydroxyalkyl group, or an alkynyl group, or Rand Rform, together with the nitrogen atom adjacent thereto, a nitrogen-containing saturated heterocyclic group which may have a substituent) and a drug composition containing the compound. The compound exhibits tumor necrosis factor (TNF-α) production inhibitory effect and improved absorption upon oral administration.