The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2008
Filed:
May. 19, 2003
Domenico Maglione, 03012 Anagni FR, IT;
Mauro Battisti, 00032 Carpineto RM, IT;
Ettore Conti, 03012 Rocca di Papa RM, IT;
Giuseppe Salvia, 95123 Catania CT, IT;
Marina Tucci, 03012 Anagni FR, IT;
Alberto Mion, 03100 Frosinone FR, IT;
Domenico Maglione, 03012 Anagni FR, IT;
Mauro Battisti, 00032 Carpineto RM, IT;
Ettore Conti, 03012 Rocca di Papa RM, IT;
Giuseppe Salvia, 95123 Catania CT, IT;
Marina Tucci, 03012 Anagni FR, IT;
Alberto Mion, 03100 Frosinone FR, IT;
Other;
Abstract
The present invention relates to chemically stable muteins of type 1 Placental Growth Factor (PLGF-1) bearing the substitution or elimination of a cysteine residue from the wild type protein amino acid sequence, their preparation, their therapeutic and cosmetic uses, and pharmaceutical and cosmetic compositions containing said derivatives. The invention likewise relates to the production of antibodies for said derivatives and their use in the diagnosis and treatment of tumoral and non-tumoral pathologies.