The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2008
Filed:
Jan. 20, 2004
Ali O. Gure, New York, NY (US);
Elisabeth Stockert, New York, NY (US);
Matthew J. Scanlan, New York, NY (US);
Dirk Jager, New York, NY (US);
Lloyd J. Old, New York, NY (US);
Yao-tseng Chen, New York, NY (US);
Ali O. Gure, New York, NY (US);
Elisabeth Stockert, New York, NY (US);
Matthew J. Scanlan, New York, NY (US);
Dirk Jager, New York, NY (US);
Lloyd J. Old, New York, NY (US);
Yao-Tseng Chen, New York, NY (US);
Ludwig Institute for Cancer Research, New York, NY (US);
Memorial Sloan-Kettering Cancer Center, New York, NY (US);
New York Hospital-Cornell Medical Center, New York, NY (US);
Abstract
Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in small cell lung cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens expressed in patients afflicted with small cell lung cancer. The invention provides, among other things, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected with those molecules. The invention also provides isolated proteins and peptides, antibodies to those proteins and peptides and cytotoxic T lymphocytes which recognize the proteins and peptides. Fragments of the foregoing including functional fragments and variants also are provided. Kits containing the foregoing molecules additionally are provided. The molecules provided by the invention can be used in the diagnosis, monitoring, research, or treatment of conditions characterized by the expression of one or more cancer associated antigens.