The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2008
Filed:
Jul. 21, 2003
Gerardo Castillo, Seattle, WA (US);
Paula Y. Choi, Bellevue, WA (US);
Beth Nguyen, Bothell, WA (US);
Alan D. Snow, Lynnwood, WA (US);
Gerardo Castillo, Seattle, WA (US);
Paula Y. Choi, Bellevue, WA (US);
Beth Nguyen, Bothell, WA (US);
Alan D. Snow, Lynnwood, WA (US);
Other;
Abstract
Assay-guided affinity fractionation and reverse phase high pressure liquid chromatography (HPLC) methodology to isolate, test and characterize the most active water-soluble ingredients within Cat's Claw, or. These components appear to account for the majority of the amyloid or Aβ fibrillogenesis inhibitory activity. Individual fractions and/or compounds as isolated by HPLC are tested in relevant in vitro and/or animal models, and found to consistently demonstrate inhibition of amyloid or Aβ fibrillogenesis. Related extraction methods are disclosed.