The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2008

Filed:

Sep. 22, 2005
Applicants:

Daniel D. Smolko, Jamul, CA (US);

Paul D. Swanson, Santee, CA (US);

Dalibor Hodko, Poway, CA (US);

David Canter, San Diego, CA (US);

Robert W. Haigis, San Diego, CA (US);

Tricia Patterson, San Diego, CA (US);

Inventors:

Daniel D. Smolko, Jamul, CA (US);

Paul D. Swanson, Santee, CA (US);

Dalibor Hodko, Poway, CA (US);

David Canter, San Diego, CA (US);

Robert W. Haigis, San Diego, CA (US);

Tricia Patterson, San Diego, CA (US);

Assignee:

Nanogen, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for the transport and hybridization of a nucleic acid on an electrode device by providing a low conductivity buffer with a reducing agent to the device. The low conductivity buffer may also contain a zwitterion. A current and voltage is applied to a location of the device to effect electrophoretic transportation of the nucleic acid towards the location. The nucleic acid is then hybridized to a nucleic probed located at the location. The reducing agent in the low conductivity buffer may also be acting as a chaotropic agent.


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