The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2007
Filed:
Dec. 21, 2001
Helene Crassier, Weiterstadt, DE;
Uwe Eckert, Darmstadt, DE;
Henning Boettcher, Darmstadt, DE;
Andreas Bathe, Darmstadt, DE;
Steffen Emmert, Weiterstadt, DE;
Helene Crassier, Weiterstadt, DE;
Uwe Eckert, Darmstadt, DE;
Henning Boettcher, Darmstadt, DE;
Andreas Bathe, Darmstadt, DE;
Steffen Emmert, Weiterstadt, DE;
Merck Patent Gesellschaft Mit Beschrankter Haftung, Darmstadt, DE;
Abstract
The present invention relates to a process for the preparation of (3-cyano-1H-indol-7-yl)[4-(4-fluorophenethyl)piperazin-1-yl]-methanone and salts thereof, characterised in that an indole ester of the formula II in which R is as defined in Claim 1, is converter into 3-cyano-1H-indole-7-carboxylic acid via steps (1) to (4) according to Claim 1, and this is reacted with 1-[2-(4-fluorophenyl)ethyl]piperazine of salts thereof to give the product.