The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2007

Filed:

Apr. 09, 2004
Applicants:

Gene G.-y. Shen, Diamond Bar, CA (US);

Yuan Lin, Walnut, CA (US);

Josephine M. Michael, Placentia, CA (US);

Inventors:

Gene G.-Y. Shen, Diamond Bar, CA (US);

Yuan Lin, Walnut, CA (US);

Josephine M. Michael, Placentia, CA (US);

Assignee:

Beckman Coulter, Inc., Fullerton, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/04 (2006.01); C12Q 1/68 (2006.01); C12P 19/34 (2006.01); C07F 9/02 (2006.01); C07D 473/00 (2006.01); C07F 9/06 (2006.01); C07D 471/02 (2006.01); G03G 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Fluorescent labeled reporter compounds having a modified cyanine dye that is coupled to a nucleotide derivative through a linker are disclosed. The compounds are useful for nucleic acid sequence analysis. The fluorescent labeled reporter compounds are ring-locked cyanine dyes that are coupled to a nucleotide derivative, such as a modified DNA base, through a linker. These fluorescent labeled reporter compounds can be used as DNA chain-terminators in DNA synthesis to generate DNA fragments that are fluorescently-labeled at the 3'-terminal end of the DNA fragment.


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