The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2007
Filed:
Jul. 29, 2004
Seth D. Rose, Tempe, AZ (US);
Karl J. Okolotowicz, Goleta, CA (US);
Rosemarie F. Hartman, Tempe, AZ (US);
Jason Houtchens, Tempe, AZ (US);
Seth D. Rose, Tempe, AZ (US);
Karl J. Okolotowicz, Goleta, CA (US);
Rosemarie F. Hartman, Tempe, AZ (US);
Jason Houtchens, Tempe, AZ (US);
Arizona Biomedical Research Commission, Phoenix, AZ (US);
Abstract
Conjugated nitro alkene compounds hamper or prevent proliferation of cancer cells in cell culture and in cancer patients, which can result in a decrease in tumor size and/or disappearance of the cancer. The compounds may act by interference with cancer cell biochemistry, in which isoprenoid groups such as farnesyl and geranylgeranyl become bonded to various oncogenic proteins such as Ras, RhoA, RhoB, or some other growth-related cellular protein(s).