The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2007
Filed:
Feb. 04, 2004
Mark M. Mazumder, Little Rock, AR (US);
Jawahar L. Mehta, Little Rock, AR (US);
Malay K. Mazumder, Little Rock, AR (US);
Nawab Ali, Little Rock, AR (US);
Steven Trigwell, Merritt Island, FL (US);
Rajesh Sharma, Little Rock, AR (US);
Samiran DE, Little Rock, AR (US);
Mark M. Mazumder, Little Rock, AR (US);
Jawahar L. Mehta, Little Rock, AR (US);
Malay K. Mazumder, Little Rock, AR (US);
Nawab Ali, Little Rock, AR (US);
Steven Trigwell, Merritt Island, FL (US);
Rajesh Sharma, Little Rock, AR (US);
Samiran De, Little Rock, AR (US);
Board of Trustees of the University of Arkansas, Little Rock, AR (US);
Abstract
An encased stent that discourages restenosis by having a homogenous endothelial cell lining along the inner wall of the stent. The endothelial cell lining may be coated on the stent before the stent is placed in the artery, or the endothelial cell lining may be grown after placement by several factors that encourage such growth and discourage restenosis. The endothelial cells to coat the stent may be genetically modified to enhance the growth of the endothelial cells into a homogeneous lining. The stent has a continuous lining in the form of a multi-layer polymer coating, including a conducting biocorrosion inhibiting layer and a continuous film of polyurethane coupled by a coupling agent to polyethylene glycol. Various drugs and cell factors may be incorporated into the lining, such as anti-thrombin, anti-inflammatory and anti-coagulant drugs, cell cycle inhibitors, and vascular endothelial growth factors.