The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 18, 2007

Filed:

Jan. 12, 2006
Applicants:

Zbigniew Majka, Lubzina, PL;

Katarzyna Ewa Rusin, Warszawa, PL;

Dominik Daniel Kludkiewicz, Adamed, PL;

Krzysztof Kurowski, Siedlce, PL;

Katarzyna Joanna Matusiewicz, Lwowek Slaski, PL;

Tomasz Stawinski, Wiasowna, PL;

Daniel Sulikowski, Gubin, PL;

Piotr Kowalczyk, Warszawa, PL;

Inventors:

Zbigniew Majka, Lubzina, PL;

Katarzyna Ewa Rusin, Warszawa, PL;

Dominik Daniel Kludkiewicz, Adamed, PL;

Krzysztof Kurowski, Siedlce, PL;

Katarzyna Joanna Matusiewicz, Lwowek Slaski, PL;

Tomasz Stawinski, Wiasowna, PL;

Daniel Sulikowski, Gubin, PL;

Piotr Kowalczyk, Warszawa, PL;

Assignee:

Adamed Sp. z.o.o, Czosnow K/Warszawy, PL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 277/42 (2006.01); C07D 263/38 (2006.01); C07D 233/84 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to new compounds, being 3-phenylpropionic acid derivatives of formula I wherein W represents COOH group or its bioisosters, or —COO—C–C-alkyl group; Y represents NH, N—C–C-alkyl, O, or S; Z represents NH, N—C–C-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C–C-alkyl, N-aryl, NSO—C–C-alkyl, N—SO-aryl, or N—SO-heteroaryl; R, to Reach independently represent hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof. The compounds are the ligands of PPAR-gamma receptor and are useful as medicaments.


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