The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2007
Filed:
Jun. 03, 2005
Ursula Schindler, Bad Soden, DE;
Hartmut Strobel, Liederbach, DE;
Peter Schindler, Bad Soden, DE;
Alexander Muelsch, Heidelberg, DE;
Ursula Schindler, Bad Soden, DE;
Hartmut Strobel, Liederbach, DE;
Peter Schindler, Bad Soden, DE;
Alexander Muelsch, Heidelberg, DE;
Sanofi-Aventis Deutschland GmbH, Frankfurt Am Main, DE;
Abstract
The invention relates to methods for detecting a soluble guanylate cyclase whose heme iron is in the trivalent oxidation state, and to methods for finding chemical substances which stimulate the activity of a soluble guanylate cyclase when the heme iron of at least part of this soluble guanylate cyclase is oxidized to the trivalent state and also to diagnostic aids or kits for detecting a soluble guanylate cyclase with trivalent heme iron. Further, the invention relates methods for detecting a soluble guanylate cyclase lacking a heme group, and to methods for finding chemical substances which stimulate the activity of a soluble guanylate cyclase lacking a heme group.