The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2007
Filed:
Aug. 26, 2003
Magnus Von Knebel Doeberitz, Ziegelhausen, DE;
Rüdiger Ridder, Schriesheim, DE;
Matthias Herkert, Heidelberg, DE;
Anja Reichert, Nuβloch, DE;
Magnus Von Knebel Doeberitz, Ziegelhausen, DE;
Rüdiger Ridder, Schriesheim, DE;
Matthias Herkert, Heidelberg, DE;
Anja Reichert, Nuβloch, DE;
MTM Laboratories AG, Heidelberg, DE;
Abstract
The present invention relates to a method for the early diagnosis of carcinomas and their preliminary stages, which comprises determining the overexpression of a cell cycle regulatory protein in a solubilized body sample. The present invention is particularly directed to a method for detecting cervical carcinomas, cervical intraepithelial neoplasias, or cervical carcinomas in-situ from a solubilized cervical body sample of a human subject, by solubilizing the cervical body sample in a lysis buffer, and determining the overexpression of cyclin dependent kinase inhibitor p16 in the solubilized cervical sample. The invention also concerns a test kit usable for this purpose as well as an in-vitro diagnostic device.