The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2007

Filed:

Mar. 24, 2004
Applicants:

Lauren O. Bakaletz, Hilliard, OH (US);

Robert S. Munson, Jr., Hilliard, OH (US);

Inventors:

Lauren O. Bakaletz, Hilliard, OH (US);

Robert S. Munson, Jr., Hilliard, OH (US);

Assignee:

Children's Hospital, Inc., Columbus, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a mutation within the sap operon of an avirulent clone of a nontypeable strain of(NTHi). The invention also relates to the NTHi sap operon genes and the polypeptides encoded by these polynucleotide sequences. The invention also relates to a novel 110 kDa NTHi outer membrane protein and the polynucleotide that encodes this outer membrane protein. Methods of screening for NTHi infection, and treating and preventing NTHi related disorders are also contemplated.


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