The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2007
Filed:
Jul. 12, 2002
Akio Matsushita, Yamaguchi, JP;
Mizuho Oda, Yamaguchi, JP;
Yasuhiro Kawachi, Yamaguchi, JP;
Jun-ichi Chika, Yamaguchi, JP;
Akio Matsushita, Yamaguchi, JP;
Mizuho Oda, Yamaguchi, JP;
Yasuhiro Kawachi, Yamaguchi, JP;
Jun-ichi Chika, Yamaguchi, JP;
AstraZeneca UK Limited, London, GB;
Abstract
A 2-(N-methyl-N-methanesulfonylamino)pyrimidine compound of the formula (3): [R is a hydrocarbyl group], is prepared by the steps of: (I) reacting an isobutyrylacetate ester with 4-fluorobenzaldehyde and urea in the presence of a protonic compound and a metal salt; (II) oxidizing the reaction product of the step (I); (III) reacting the oxidation product of the step (II) with an organic sulfonyl halide or an organic sulfonyl anhydride; and (IV) reacting the reaction product of the step (III) with N-methyl-N-methanesulfonamide.