The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2007
Filed:
Jun. 20, 2003
Kenneth P. Murphy, St. Louis, MO (US);
Norihiko Watanabe, Chiba, JP;
Theresa L. Murphy, St. Louis, MO (US);
Jianfei Yang, Sandy Hook, CT (US);
Kenneth P. Murphy, St. Louis, MO (US);
Norihiko Watanabe, Chiba, JP;
Theresa L. Murphy, St. Louis, MO (US);
Jianfei Yang, Sandy Hook, CT (US);
Washington University in St. Louis, St. Louis, MO (US);
Abstract
The present invention provides a novel lymphocyte inhibitory receptor termed BTLA which is expressed on both T and B cells, and identifies B7 family member B7as interacting with BTLA to attenuate lymphocyte activity. Methods and compositions for modulating BTLA-mediated negative signaling and interfering with the interaction of BTLA and B7for therapeutic, diagnostic and research purposes are also provided.