The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2007
Filed:
Aug. 23, 2004
Takehiro Fukami, Tsukuba, JP;
Akio Kanatani, Tsukuba, JP;
Akane Ishihara, Tsukuba, JP;
Yasuyuki Ishii, Tsukuba, JP;
Toshiyuki Takahashi, Tsukuba, JP;
Yuji Haga, Tsukuba, JP;
Toshihiro Sakamoto, Tsukuba, JP;
Takahiro Itoh, Okazaki, JP;
Masato Chiba, Tsukuba, JP;
Takehiro Fukami, Tsukuba, JP;
Akio Kanatani, Tsukuba, JP;
Akane Ishihara, Tsukuba, JP;
Yasuyuki Ishii, Tsukuba, JP;
Toshiyuki Takahashi, Tsukuba, JP;
Yuji Haga, Tsukuba, JP;
Toshihiro Sakamoto, Tsukuba, JP;
Takahiro Itoh, Okazaki, JP;
Masato Chiba, Tsukuba, JP;
Banyu Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
Compounds represented by the general formula (I) wherein Arrepresents an aryl or heteroaryl which may be substituted; n represents 0 or 1; T, U, V and W each independently represent a nitrogen atom or a methine group which may have a substituent selected from the group consisting of halogen, lower alkyl, hydroxy and lower alkoxy, wherein at least two of which represent said methine group; X represents methine, hydroxy substituted methine or nitrogen atom; Y represents an imino which may be substituted with lower alkyl, or oxygen; and a salt, ester or N-oxide derivative thereof. The compounds exhibit NPY antagonistic activities and are useful as agents for the treatment of various diseases related to NPY, for example, cardiovascular disorders, central nervous system disorders, metabolic diseases, sexual and reproductive dysfunctions, gastro-intestinal disorders, respiratory disorders, inflammation or glaucoma, and the like.