The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2007
Filed:
Aug. 12, 2003
John Cochran, Marshfield, MA (US);
Jeremy Green, Burlington, MA (US);
Michael R. Hale, Bedford, MA (US);
Brian Ledford, Attleboro, MA (US);
Francois Maltais, Tewksbury, MA (US);
Suganthini Nanthakumar, Newton, MA (US);
John Cochran, Marshfield, MA (US);
Jeremy Green, Burlington, MA (US);
Michael R. Hale, Bedford, MA (US);
Brian Ledford, Attleboro, MA (US);
Francois Maltais, Tewksbury, MA (US);
Suganthini Nanthakumar, Newton, MA (US);
Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);
Abstract
Described herein are compounds that are useful as protein kinase inhibitors having the formulae I and V: or a pharmaceutically acceptable salt thereof, wherein Ring B, Z, Z, U, T, m, n, p, Q, Q', R, R, R, R, and Rare as defined herein. These compounds, and pharmaceutically acceptable compositions thereof, are useful for treating or lessening the severity of a variety of disorders, including stroke, inflammatory disorders, autoimmune diseases such as SLE lupus and psoriasis, proliferative disorders such as cancer, and conditions associated with organ transplantation.