The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 04, 2007

Filed:

Feb. 11, 2004
Applicants:

Raghavan Rajagopalan, Beechwood, OH (US);

Samuel I. Achilefu, St. Louis, MO (US);

Joseph E. Bugaj, St. Charles, MO (US);

Richard B. Dorshow, St. Louis, MO (US);

Inventors:

Raghavan Rajagopalan, Beechwood, OH (US);

Samuel I. Achilefu, St. Louis, MO (US);

Joseph E. Bugaj, St. Charles, MO (US);

Richard B. Dorshow, St. Louis, MO (US);

Assignee:

Mallinckrodt, Inc, St. Louis, MO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/533 (2006.01); G01N 21/76 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses dye-azide derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds of the present invention may contain either a mixture of Type 1 and Type 2 agents or a single entity that integrates both units in the same molecules. The compounds are designed to produce both Type 1 and Type 2 phototherapeutic effect at once using dual wavelength light source that will produce singlet oxygen and nitrene at the lesion of interest.


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