The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2007
Filed:
Jan. 07, 2003
Emmanuel Le Poul, Brussels, BE;
Michel Detheux, Mons, BE;
Stéphane Brézillon, Brussels, BE;
Vincent Lannoy, Liernu, BE;
Marc Parmentier, Beersel, BE;
Emmanuel Le Poul, Brussels, BE;
Michel Detheux, Mons, BE;
Stéphane Brézillon, Brussels, BE;
Vincent Lannoy, Liernu, BE;
Marc Parmentier, Beersel, BE;
Euroscreen S.A., , BE;
Abstract
The present invention is related to the G-protein coupled orphan receptor GPR43 and the identification of short chain fatty acids as natural ligands of the receptor. The invention further relates to assays for the identification of agents that modulate GPR43 ligand binding and signaling activity, as well as compositions consisting essentially of an isolated GPR43 polypeptide and an isolated short chain fatty acid. The invention also relates to diagnostic methods and kits that take advantage of the novel interaction of GPR43 with short chain fatty acids.