The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 04, 2007
Filed:
Nov. 02, 2000
Herwig Brunner, Weilheim, DE;
Jürgen Bernhagen, Aachen, DE;
Robert Kleemann, Leiden, NL;
Ralf Mischke, Biberach, DE;
Afroditi Kapurniotu, Aachen, DE;
Herwig Brunner, Weilheim, DE;
Jürgen Bernhagen, Aachen, DE;
Robert Kleemann, Leiden, NL;
Ralf Mischke, Biberach, DE;
Afroditi Kapurniotu, Aachen, DE;
Abstract
The present invention relates to methods for screening molecules and methods to detect protein-protein interactions and means used therein. More specifically, the present invention relates to methods for screening candidate drugs for treating or detecting MIF (macrophage migration inhibitor factor) related diseases. In certain aspects, the present invention involves detecting MIF/Jab1 (c-Jun activation domain binding protein) interactions as a basis for modulating cellular regulatory pathways and for identifying candidate drugs for MIF-related diseases. The invention also provides methods for the identification of molecules which dissociate or prevent interaction or binding between MIF and Jab1.