The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2007

Filed:

Jan. 20, 2006
Applicants:

Yukiyoshi Yamazaki, Higashimurayama, JP;

Tsutomu Toma, Kodaira, JP;

Masahiro Nishikawa, Nagoya, JP;

Hajime Yamada, Higashimurayama, JP;

Hidefumi Ozawa, Hachiouji, JP;

Ayumu Okuda, Higashimurayama, JP;

Kazutoyo Abe, Mitaka, JP;

Inventors:

Yukiyoshi Yamazaki, Higashimurayama, JP;

Tsutomu Toma, Kodaira, JP;

Masahiro Nishikawa, Nagoya, JP;

Hajime Yamada, Higashimurayama, JP;

Hidefumi Ozawa, Hachiouji, JP;

Ayumu Okuda, Higashimurayama, JP;

Kazutoyo Abe, Mitaka, JP;

Assignee:

Kowa Co., Ltd., Nagoya-shi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/58 (2006.01); A61K 31/423 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a compound selectively activating PPARα, which is useful as a medicament. The present invention is specifically directed to a benzoic acid derivative represented by the following general formula (1): wherein A represents an oxygen atom, a nitrogen atom, or a sulfur atom; R represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkyl-alkyl group, an aryl group, an aryl-alkyl group an aryl-oxy-alkyl group, a pyridyl-alkyl group, an alkoxycarbonyl-alkyl group, or a carboxy-alkyl group; X represents an oxygen atom, an NH group, or an S(O)group (wherein n represents an integer of 0, 1, or 2); and m represents an integer from 2 to 8; or a salt thereof. The present invention also provides a medicament comprising the benzoic acid derivative or the salt thereof as an active ingredient.


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