The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 27, 2007

Filed:

Sep. 10, 2004
Applicants:

James B. Mcalpine, Montreal, CA;

Chris M. Farnet, Outremont, CA;

Emmanuel Zazopoulos, Montreal, CA;

Dan Sorensen, Montreal, CA;

Inventors:

James B. McAlpine, Montreal, CA;

Chris M. Farnet, Outremont, CA;

Emmanuel Zazopoulos, Montreal, CA;

Dan Sorensen, Montreal, CA;

Assignee:

Ecopia Biosciences, Inc., Saint Laurent, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 15/00 (2006.01); C07D 237/00 (2006.01); C12P 19/60 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel polyene polyketides, their pharmaceutically acceptable salts, prodrugs and derivatives have been found to have antibiotic activity. One method for obtaining the compounds is by cultivation ofATCC™ 43491 or a mutant or variant such as the strain IDAC-220604-1. Another method for obtaining the compounds is post-biosynthesis chemical modification of the compounds obtained by cultivation. Novel polynucleotide sequences and encoded proteins for the biosynthesis of the polyene polyketides are also presented.


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