The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2007

Filed:

Apr. 08, 2005
Applicants:

Vladimir P. Drachev, West Lafayette, IN (US);

Vladimir Shalaev, West Lafeyette, IN (US);

Dongmao Zhang, West Lafayette, IN (US);

Dor Ben-amotz, West Lafayette, IN (US);

Inventors:

Vladimir P. Drachev, West Lafayette, IN (US);

Vladimir Shalaev, West Lafeyette, IN (US);

Dongmao Zhang, West Lafayette, IN (US);

Dor Ben-Amotz, West Lafayette, IN (US);

Assignee:

Purdue Research Foundation, West Lafayette, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01J 3/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

Instruments for molecular detection at the nano-molar to femto-molar concentration level include a longitudinal capillary column () of known wall thickness and diameter. The column () contains a medium () including a target molecule () and a plurality of optically interactive dielectric beads () on the order of about 10meters up to about 10meters and/or metal nanoparticles () on the order of 1-500 nm. A flow inducer () causes longitudinal movement of the target molecule within the column (). A laser () introduces energy laterally with respect to the column () at a wavelength and in a direction selected to have a resonant mode within the capillary column wall () and couple to the medium (). A detector () is positioned to detect Raman scattering occurring along the column () due to the presence of the target molecule.


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