The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 20, 2007

Filed:

Mar. 19, 2002
Applicants:

Malcolm Berry, Stevenage, GB;

John C. Roberts, Durham, NC (US);

Shiping Xie, Durham, NC (US);

Inventors:

Malcolm Berry, Stevenage, GB;

John C. Roberts, Durham, NC (US);

Shiping Xie, Durham, NC (US);

Assignee:

Glaxo Group Limited, Greenford, Middlesex, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 19/167 (2006.01);
U.S. Cl.
CPC ...
Abstract

An improved process for preparing N6 -substituted aminopurine ribofuranose nucleosides. Compounds of this type are known to be usefull in the prepartation of compounds having activitity at adenosine receptors, e.g. Adenosine A1 receptor. The process comprises the step of reacting a 6-halopurine ribofuranose nucleoside with an amine in the presence of CaCO3 , wherein acid is added to the reaction mixture.


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