The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 20, 2007
Filed:
Aug. 30, 2002
Vasilios Bavetsias, Sutton, GB;
Ann L Jackman, Horsham, GB;
Vasilios Bavetsias, Sutton, GB;
Ann L Jackman, Horsham, GB;
BTG International Limited, London, GB;
Abstract
Cyclopenta[g]quinazolines of the formula (I):—wherein: A is a group OR or NRRwherein Rand Rare each independently hydrogen Calkyl, Calkenyl, Calkynyl, Chydroxyalkyl, Chalogenoalkyl or Ccyanoalkyl, or Rand Rtogether with the intermediate N form a five- or six-membered heterocyclic ring, p is an integer in the range 1 to 4, Ris hydrogen, Calkyl, Calkenyl, Calkynyl, Chydroxyalkyl, Chalogenoalkyl or Ccyanoalkyl; Aris phenylene, thiophenediyl, thiazolediyl, pyridinediyl or pyrimidinediyl which may optionally bear one or two substituents selected from halogeno, hydroxy, amino, nitro, cyano, trifluoromethyl, Calkyl and Calkoxy, and Ris a group of one of the following formulae: -A-Ar-A-Y-A-CON(R)CH(Y)Y-A-X—Arand pharmaceutically acceptable salts or esters thereof are of therapeutic value particularly in the treatment of cancer