The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2007

Filed:

Apr. 05, 2002
Applicants:

Kai Schiemann, Darmstadt, DE;

Henning Böttcher, Darmstadt, DE;

Joachim Leibrock, Pfungstadt, DE;

Inventors:

Kai Schiemann, Darmstadt, DE;

Henning Böttcher, Darmstadt, DE;

Joachim Leibrock, Pfungstadt, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/424 (2006.01); A61K 31/445 (2006.01); A61K 31/5377 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 498/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of the formula I in which R, R, Rand Rare as defined in claim 1, are ligands of the nicotinic acetylcholine receptor and/or serotonergic ligands and are suitable for the prophylaxis or treatment of psychoses, schizophrenia, depression, anxiety states, dementia, in particular Alzheimer's disease and Lewy bodies dementia, neurodegenerative disorders, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, Tourette's syndrome, learning and memory restrictions, bulimia anorexia nervosa or other eating disorders, compulsvie behaviour, premenstrual syndrome, age-induced memory impairment, amelioration of withdrawal symptoms in nicotine dependence, strokes or brain damage by toxic compounds, and for the treatment of disorders which are characterised by an excess of circulating serotonin or by serotonergic hyperactivity


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