The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2007
Filed:
Jul. 03, 2003
R. Rogers Yocum, Lexington, MA (US);
Thomas A. Patterson, North Attleboro, MA (US);
Janice G. Pero, Lexington, MA (US);
Theron Hermann, Kinnelon, NJ (US);
R. Rogers Yocum, Lexington, MA (US);
Thomas A. Patterson, North Attleboro, MA (US);
Janice G. Pero, Lexington, MA (US);
Theron Hermann, Kinnelon, NJ (US);
BASF Aktiengesellschaft, , DE;
Abstract
The present invention features improved methods for the enhanced production of pantoate and pantothenate utilizing microorganisms having modified pantothenate biosynthetic enzyme activities and having modified methylenetetrahydrofolate (MTF) biosynthetic enzyme activities. In particular, the invention features methods for enhancing production of desired products by increasing levels of a key intermediate, ketopantoate, by increasing enzymes or substrates that contribute directly or indirectly to its synthesis. Recombinant microorganisms and conditions for culturing same are also are featured. Also featured are compositions produced by such microorganisms.