The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 06, 2007
Filed:
Apr. 21, 2004
Genetically modified cells and methods for converting (r)-methylmalonyl coa to (s)-methylmalonyl coa
Applicants:
Daniel Santi, San Francisco, CA (US);
Linda Dayem, San Anselmo, CA (US);
James Kealey, San Anselmo, CA (US);
Inventors:
Daniel Santi, San Francisco, CA (US);
Linda Dayem, San Anselmo, CA (US);
James Kealey, San Anselmo, CA (US);
Assignee:
KOSAN Biosciences, Inc., Hayward, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/62 (2006.01);
U.S. Cl.
CPC ...
Abstract
Recombinanthost cells that comprise recombinant DNA expression vectors that drive expression of methylmalonyl CoA mutase fromoras well asepimerase can produce S-methylmalonyl CoA, a required substrate for the production of polyketides by most modular polyketide synthases not present in wild-typehost cells.