The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 06, 2007

Filed:

Feb. 13, 2006
Applicants:

Paul J. Lawrence, Campbell, CA (US);

Mark A. Hughes, Morgan Hill, CA (US);

Aulena Chaudhuri, San Jose, CA (US);

Terrence J. Andreasen, San Jose, CA (US);

Inventors:

Paul J. Lawrence, Campbell, CA (US);

Mark A. Hughes, Morgan Hill, CA (US);

Aulena Chaudhuri, San Jose, CA (US);

Terrence J. Andreasen, San Jose, CA (US);

Assignee:

Quidel Corporation, San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The release by trichomonads of a hydrolase that hydrolyzes a narrowly defined class of substrates at a low pH without interference from hydrolases that are unrelated to trichomoniasis is the basis for a selective diagnostic assay for trichomoniasis that measures hydrolysis of any of these substrates by vaginal fluid at a low pH. Selective assays for trichomoniasis are also obtained by removing particulate matter from a sample of vaginal fluid to extract a fraction devoid of particles greater than a selected size, and where desired, combining the extracted fraction with any of certain specified hydrolase inhibitors, then testing the fraction for enzymatic hydrolase activity. These qualities of trichomoniasis are the basis for a series of diagnostic tests and test devices that produce results that are detectable by visual and other means with a high degree of accuracy.


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