The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 30, 2007

Filed:

Jun. 23, 2006
Applicants:

Chi-tang Ho, East Brunswick, NJ (US);

Geetha Ghai, Murray Hill, NJ (US);

Shengmin Sang, East Brunswick, NJ (US);

Jin-woo Jhoo, Little Rock, AR (US);

Mou-tuan Huang, Englewood Cliffs, NJ (US);

Robert T. Rosen, Monroe Township, NJ (US);

Slavik Dushenkov, Fort Lee, NJ (US);

Inventors:

Chi-Tang Ho, East Brunswick, NJ (US);

Geetha Ghai, Murray Hill, NJ (US);

Shengmin Sang, East Brunswick, NJ (US);

Jin-Woo Jhoo, Little Rock, AR (US);

Mou-Tuan Huang, Englewood Cliffs, NJ (US);

Robert T. Rosen, Monroe Township, NJ (US);

Slavik Dushenkov, Fort Lee, NJ (US);

Assignees:

Wellgen, Inc., New Brunswick, NJ (US);

Rutgers, The State University of New Jersey, New Brunswick, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 45/00 (2006.01); C07C 49/115 (2006.01); C07D 311/78 (2006.01); C07D 315/00 (2006.01); A61K 31/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective antioxidant and anti-inflammatory agents. The present invention also provides novel method of synthesizing benzotropolone compounds in high yields and method of treating inflammatory conditions using benzotropolone containing compounds.


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