The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2007
Filed:
Sep. 02, 2005
Zaihui Zhang, Vancouver, CA;
Gregory B Chopiuk, San Diego, CA (US);
Timothy S Daynard, Vancouver, CA;
Shisen Wang, Coquitlam, CA;
Zaihui Zhang, Vancouver, CA;
Gregory B Chopiuk, San Diego, CA (US);
Timothy S Daynard, Vancouver, CA;
Shisen Wang, Coquitlam, CA;
QLT Inc., Vancouver, CA;
Abstract
This invention is directed to methods of using compounds having the structure: and including stereoisomers, solvates, and pharmaceutically acceptable salts thereof, wherein each of R, R, Rand Ris independently selected from hydrogen, R, R, and R; Ris selected from alkyl, heteroalkyl, aryl and heteroaryl; Ris selected from (R)-alkylene, (R)-heteroalkylene, (R)-arylene and (R)-heteroarylene; Ris selected from (R)-alkylene, (R)-heteroalkylene, (R)-arylene, and (R)-heteroarylene; and n is selected from 0, 1, 2, 3, 4 and 5, where Rand Rmay together form a heterocyclic structure including the nitrogen to which they are both attached, and Rand Rmay together form a heterocyclic structure including the nitrogen to which they are both attached; and each of Land Lis independently selected from -A1-A2-A3- where each of A1, A2, and A3 is independently selected from a direct bond, alkylene, heteroalkylene, arylene and heteroarylene. These compounds are useful in treating hyperproliferative disorders and inducing apoptosis.