The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 2007
Filed:
Oct. 20, 2003
Che-ming Teng, Taipei, TW;
Hui-po Wang, Taipei, TW;
Eric I. C. LI, Tainan, TW;
On Lee, Taipei, TW;
Jih-hwa Guh, Taipei, TW;
Huei-ting Chen, Taipei, TW;
Ya-bing Fan, Taipei, TW;
Ya-lan Chen, Tainan, TW;
Che-Ming Teng, Taipei, TW;
Hui-Po Wang, Taipei, TW;
Eric I. C. Li, Tainan, TW;
On Lee, Taipei, TW;
Jih-Hwa Guh, Taipei, TW;
Huei-Ting Chen, Taipei, TW;
Ya-Bing Fan, Taipei, TW;
Ya-Lan Chen, Tainan, TW;
AngioRx Corporation, Taipei, TW;
Abstract
This invention relates to a method for treating an angiogenesis-related disease. The method includes administering to a subject in need thereof an effective amount of a piperazinedione compound having the formula: In the above formula, each ofand, independently, is a single bond or a double bond; A is H or CH(RR) whenis a single bond, or C(RR) whenis a double bond; Z is CH(RR) whenis a single bond, or C(RR) whenis a double bond; each of Rand R, independently, is H, C(O)R, C(O)OR, C(O)NRR, or SOR; and each of R, R, R, R, R, and R, independently, is H, C-Calkyl, aryl, heteroaryl, C-Ccycloalkyl, or C-Cheterocycloalkyl; or Rand Rtaken together are C-Ccycloalkyl, C-Cheterocycloalkyl, aryl, or heteroaryl; or Rand Ror Rand Rtaken together are C-Ccycloalkyl, C-Cheterocycloalkyl, aryl, or heteroaryl; provided that one of Rand Ris aryl or heteroaryl.