The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 23, 2007
Filed:
Nov. 05, 2003
Applicants:
Gary L. Cantrell, Troy, IL (US);
Robert E. Halvachs, Belleville, IL (US);
Inventors:
Gary L. Cantrell, Troy, IL (US);
Robert E. Halvachs, Belleville, IL (US);
Assignee:
Mallinckrodt Inc., St. Louis, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/02 (2006.01); C07D 489/08 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the preparation of a quaternary derivative of the morphinan alkaloid, the process comprising contacting a tertiary N-substituted morphinan alkaloid with an alkyl halide in an anhydrous solvent system, wherein the solvent system comprises an aprotic dipolar solvent with the aprotic dipolar solvent constituting at least 25 wt. % of the solvent system.