The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 23, 2007

Filed:

Nov. 02, 2005
Applicants:

Jesse A. May, Fort Worth, TX (US);

Thomas R. Dean, Weatherford, TX (US);

Najam A. Sharif, Arlington, TX (US);

Hwang-hsing Chen, Fort Worth, TX (US);

Inventors:

Jesse A. May, Fort Worth, TX (US);

Thomas R. Dean, Weatherford, TX (US);

Najam A. Sharif, Arlington, TX (US);

Hwang-Hsing Chen, Fort Worth, TX (US);

Assignee:

Alcon Manufacturing, Ltd., Fort Worth, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/00 (2006.01); C07D 401/00 (2006.01); C07D 241/04 (2006.01); A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds with 5HTreceptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.


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