The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2007
Filed:
Dec. 29, 2003
Paolo Monaci, Rome, IT;
Maurizio Nuzzo, Rome, IT;
Nicola LA Monica, Rome, IT;
Gennaro Ciliberto, Rome, IT;
Armin Lahm, Rome, IT;
Paolo Monaci, Rome, IT;
Maurizio Nuzzo, Rome, IT;
Nicola La Monica, Rome, IT;
Gennaro Ciliberto, Rome, IT;
Armin Lahm, Rome, IT;
Istituto di Ricerche di Biologia Molecolare P. Angeletti S.p.A., Pomezia (Rome), IT;
Abstract
Polynucleotides encoding rhesus monkey HER2/neu have been isolated, cloned and sequenced. The gene encoding the HER2/neu is commonly associated with the development of epithelial-derived human carcinomas. The present invention provides compositions and methods to elicit or enhance immunity to the protein product expressed by the HER2/neu tumor-associated antigen, wherein aberrant HER2/neu expression is associated with a carcinoma or its development. This invention specifically provides adenoviral vector constructs carrying rhHER2/neu and discloses their use in vaccines and pharmaceutical compositions for preventing and treating cancer.