The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2007

Filed:

Nov. 12, 2003
Applicants:

Galla Chandra Rao, Princeton, NJ (US);

Herman Rutner, Hatboro, PA (US);

Inventors:

Galla Chandra Rao, Princeton, NJ (US);

Herman Rutner, Hatboro, PA (US);

Assignee:

Immunivest Corporation, Wilmington, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/06 (2006.01); G01N 1/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and kits for used as an internal or external control in rare cell analysis are disclosed. A plurality of fluorescently distinct sets of cells is used to define a range to assess the isolation of rare target cells from a sample. Thus, a known number of cells, expressing the surface and intracellular antigens present in the targeted rare cells, are stabilized and modified in such a way that they can be discriminated from the targeted rare cells. In addition, these cells are separated into at least two sets based upon the number. These sets are detectably distinct from each other and provide an upper and lower indication of the detection ability of the rare cell assay.


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