The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2007
Filed:
Oct. 05, 2000
Laura M. Mcintosh, St. Laurent, CA;
Michael Jackson, Winnipeg, CA;
Henry Mantsch, Ii, Winnipeg, CA;
James R. Mansfield, Boston, MA (US);
A. Neil Crowson, Winnipeg, CA;
John W. P. Toole, Winnipeg, CA;
Laura M. McIntosh, St. Laurent, CA;
Michael Jackson, Winnipeg, CA;
Henry Mantsch, II, Winnipeg, CA;
James R. Mansfield, Boston, MA (US);
A. Neil Crowson, Winnipeg, CA;
John W. P. Toole, Winnipeg, CA;
National Research Council of Canada, Ottawa, Ontario, CA;
Abstract
A non-invasive tool for skin disease diagnosis would be a useful clinical adjunct. The purpose of this study was to determine whether visible/near-infrared spectroscopy can be used to non-invasively characterize skin diseases. In-vivo visible- and near-infrared spectra (400-2500 nm) of skin neoplasms (actinic keratoses, basal cell carcinomata, banal common acquired melanocytic nevi, dysplastic melanocytic nevi, actinic lentigines and seborrheic keratoses) were collected by placing a fiber optic probe on the skin. Paired t-tests, repeated measures analysis of variance and linear discriminant analysis were used to determine whether significant spectral differences existed and whether spectra could be classified according to lesion type. Paired t-tests showed significant differences (p<0.05) between normal skin and skin lesions in several areas of the visible/near-infrared spectrum. In addition, significant differences were found between the lesion groups by analysis of variance. Linear discriminant analysis classified spectra from benign lesions compared to pre-malignant or malignant lesions with high accuracy. Visible/near-infrared spectroscopy is a promising non-invasive technique for the screening of skin diseases.