The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2007

Filed:

Dec. 10, 2004
Applicants:

Neerja Bhatnagar, Neshanic Station, NJ (US);

Pierre Broto, Romainville, FR;

Jean-francois Gourvest, Claye Souilly, FR;

Jacques Mauger, Tucson, AZ (US);

Inventors:

Neerja Bhatnagar, Neshanic Station, NJ (US);

Pierre Broto, Romainville, FR;

Jean-Francois Gourvest, Claye Souilly, FR;

Jacques Mauger, Tucson, AZ (US);

Assignee:

Aventis Pharma S.A., Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 237/04 (2006.01); A61K 31/501 (2006.01); A61K 31/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses and claims hexahydropyridazine-3-carboxylic acid hydrazides and hydrazones of formula (I) as inhibitors of proteases and kinases, and methods of using said compounds of formula (I) for the prevention or treatment of certain cardiovascular, central nervous system, inflammatory, and bone diseases as well as infectious diseases and certain cancers. Combinatorial libraries of the compounds of formula (I), pharmaceutical compositions, and methods for the preparation of combinatorial libraries and the compounds of formula (I) are also disclosed and claimed.


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