The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2007

Filed:

Dec. 20, 2002
Applicants:

Jonas Frisén, Stockholm, SE;

Ann Marie Janson, Stockholm, SE;

Clas Johansson, Stockholm, SE;

Stefan Momma, Sp{dot over (a)}nga, SE;

Diana Clarke, Stockholm, SE;

Ming Zhao, Solna, SE;

Urban Lendahl, Sundbyberg, SE;

Kioumars Delfani, Solna, SE;

Inventors:

Jonas Frisén, Stockholm, SE;

Ann Marie Janson, Stockholm, SE;

Clas Johansson, Stockholm, SE;

Stefan Momma, Sp{dot over (a)}nga, SE;

Diana Clarke, Stockholm, SE;

Ming Zhao, Solna, SE;

Urban Lendahl, Sundbyberg, SE;

Kioumars Delfani, Solna, SE;

Assignee:

NeuroNova AB, Stockholm, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a method of determining whether a test compound is a proliferation-inducing or proliferation-inhibiting agent of ependymal neural stem cells. The method comprises: (a) contacting an ependymal neural stem cell with the test compound: and (b) determining the proliferation of the ependymal neural stem cell, wherein if the proliferation of the ependymal neural stem cell is increased in the presence of the test compound as compared to the absence of the test compound, the test compound is identified as a proliferation-inducing agent or wherein if the proliferation of the ependymal neural stem cell is decreased in the presence of the test compound as compared to the absence of the test compound, the test compound is identified as a proliferation-inhibiting agent.


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