The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2007

Filed:

Apr. 16, 2004
Applicants:

William H. Andrews, Reno, NV (US);

Christopher A. Foster, Carmichael, CA (US);

Stephanie Fraser, Sparks, NV (US);

Hamid Mohammadpour, Reno, NV (US);

Laura Briggs, Reno, NV (US);

Inventors:

William H. Andrews, Reno, NV (US);

Christopher A. Foster, Carmichael, CA (US);

Stephanie Fraser, Sparks, NV (US);

Hamid Mohammadpour, Reno, NV (US);

Laura Briggs, Reno, NV (US);

Assignee:

Sierra Sciences, Inc., Reno, NV (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and compositions are provided for modulating, e.g., increasing or decreasing, the expression of telomerase reverse transcriptase (TERT). In the subject methods, the binding interaction of the GC-Box 5 repressor site with a repressor protein (or protein complex including the same) is modulated to achieve the desired change in TERT expression. The subject methods and compositions find use in a variety of different applications, including the immortalization of cells, the production of reagents for use in life science research, therapeutic applications; therapeutic agent screening applications; and the like.


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