The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2007

Filed:

Nov. 26, 2003
Applicants:

Vanitha Ramakrishnan, Belmont, CA (US);

David Powers, Fairfax, CA (US);

Dale E. Johnson, Emeryville, CA (US);

Ursula Jeffry, Redwood City, CA (US);

Vinay Bhaskar, San Francisco, CA (US);

Inventors:

Vanitha Ramakrishnan, Belmont, CA (US);

David Powers, Fairfax, CA (US);

Dale E. Johnson, Emeryville, CA (US);

Ursula Jeffry, Redwood City, CA (US);

Vinay Bhaskar, San Francisco, CA (US);

Assignee:

PDL Biopharma, Inc., Fremont, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/18 (2006.01); A61K 39/40 (2006.01); A61K 39/395 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides chimeric and humanized antibodies that specifically recognize α5β1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.


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