The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2007

Filed:

Feb. 16, 2006
Applicants:

Shigenori Ohkawa, Takatsuki, JP;

Naoyuki Kanzaki, Ibaraki, JP;

Seiji Miwatashi, Hyogo, JP;

Inventors:

Shigenori Ohkawa, Takatsuki, JP;

Naoyuki Kanzaki, Ibaraki, JP;

Seiji Miwatashi, Hyogo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4436 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

An optionally N-oxidized compound represented by the formula: wherein Rrepresents hydrogen, hydrocarbon, heterocycle, amino, acyl, Rrepresents an aromatic group, Rrepresents hydrogen, pyridyl, aromatic hydrocarbon, X represents oxygen, optionally oxidized sulfur, Y represents a bond, an oxygen, optionally oxidized sulfur, a group represented by the formula NR(Rrepresents hydrogen, hydrocarbon or acyl) and Z represents a bond or a divalent acyclic hydrocarbon, or a salt thereof has an excellent adenosine Areceptor antagonistic activity and is used as an agent for preventing or treating diseases related to an adenosine Areceptor. Furthermore, the compound (I) or a salt thereof has p38 MAP kinase inhibitory activity and TNF-α inhibitory activity and is used as an agent for preventing or treating diseases related to p38 MAP kinase and diseases related to TNF-α.


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