The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2007

Filed:

Mar. 08, 2005
Applicants:

Varghese John, San Francisco, CA (US);

Jay Tung, Belmont, CA (US);

Roy Hom, San Francisco, CA (US);

Ashley Guinn, Pacifica, CA (US);

Lawrence Fang, Foster City, CA (US);

Andrea Gailunas, San Francisco, CA (US);

Shumeye S. Mamo, Oakland, CA (US);

Inventors:

Varghese John, San Francisco, CA (US);

Jay Tung, Belmont, CA (US);

Roy Hom, San Francisco, CA (US);

Ashley Guinn, Pacifica, CA (US);

Lawrence Fang, Foster City, CA (US);

Andrea Gailunas, San Francisco, CA (US);

Shumeye S. Mamo, Oakland, CA (US);

Assignee:

Elan Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

Dipeptide derived inhibitors of the β-secretase enzyme are provided which are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of Aβ peptide in a mammal. The compounds of the invention provide useful methods of treatment by administration of these inhibitors to reduce Aβ peptide formation and in pharmaceutical compositions.


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