The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2007
Filed:
Oct. 14, 2004
Rea Ravin, Rockville, MD (US);
James V. Sullivan, Bowie, MD (US);
Daniel Hoeppner, Bethesda, MD (US);
David W. Munno, Stamford, CT (US);
Ron Mckay, Bethesda, MD (US);
Rea Ravin, Rockville, MD (US);
James V. Sullivan, Bowie, MD (US);
Daniel Hoeppner, Bethesda, MD (US);
David W. Munno, Stamford, CT (US);
Ron McKay, Bethesda, MD (US);
Abstract
An apparatus and process for monitoring migratory cell proliferation with restricted migration on a substrate includes providing a substrate, coating the substrate with extracellular matrix, plating cells suspended in cell culture media on extracellular matrix, and placing intersecting channels across the extracellular matrix components by removing the extracellular matrix components from the channels to isolate islands of the extracellular matrix components on the substrate. When the cells are immersed with a fluid, migration of the cells is confined to the isolated islands of the extracellular matrix components, permitting long-term observation of a migratory population.