The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2007

Filed:

Jun. 24, 2003
Applicants:

Kazushige Moriyama, Tokyo, JP;

Tetsuji Tanimoto, Tokyo, JP;

Tatsuki Matsuno, Tokyo, JP;

Yoshihiro Ashihara, Tokyo, JP;

Inventors:

Kazushige Moriyama, Tokyo, JP;

Tetsuji Tanimoto, Tokyo, JP;

Tatsuki Matsuno, Tokyo, JP;

Yoshihiro Ashihara, Tokyo, JP;

Assignee:

Fujirebio Inc., Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/542 (2006.01); G01N 33/543 (2006.01); G01N 33/553 (2006.01); G01N 33/566 (2006.01); G01N 21/75 (2006.01); G01N 21/76 (2006.01); C12Q 1/00 (2006.01); C12N 9/00 (2006.01); C09K 3/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a chemiluminescence enhancer treated to retain favorable dispersibility of fine solid carriers and stably exert a chemiluminescence enhancing action. The invention provides a chemiluminescence enhancer used for signal detection in a solid phase immunoassay using antigen or/and antibody immobilized onto fine solid carriers dispersible in a liquid medium, consisting of a water soluble macromolecular quaternary ammonium salt, a quaternary sulfonium salt or a quaternary phosphonium salt in order to enhance emission of light caused by an enzymatic reaction of a chemiluminescent substrate having dioxetane, wherein the chemiluminescence enhancer is given an aggregation inhibition treatment of the fine solid carriers by the treatment with an oxidizing agent or a reducing agent, and a chemiluminescence method and a kit using the chemiluminescence enhancer.


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